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Primary sources : it is synthesized through three main routes: the hexokinase/glucokinase reaction (from glucose), glycogenolysis (from glycogen stores), or the Leloir pathway (from galactose)

Similarly, chronic inflammatory diseases, such as scleroderma, 63 ulcerative colitis, 64 and Crohn's disease, 65 all predispose to the onset of cancer

"Dietary antioxidants confer significant protection to gut epithelial cells from pro-apoptotic oxidant stress" (Miller et al., 2001)

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