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Although the gcs1 and glr gene expression levels were not significantly different in ATCC18224 strain, we detected differential expression levels of these genes in the ATCC200051 strain background

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It seems likely that the spike in IL-6 , secreted by the macrophages responding to the viral entry, triggers NETosis in the patients with severe COVID-19, leading to a complex interaction among NETosis, complement and coagulation pathways [18], pulmonary immune thrombosis and acute respiratory distress

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