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They are defined as pattern-recognition receptors (PRRs), that immediately recognize specific conserved molecular components on the surfaces of pathogens (pathogen-associated molecular patterns, PAMPs) or endogenous molecules released from damaged cells (danger-associated molecular patterns, DAMPs) (Medzhitov and Janeway 2000

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References Chu L, Wang C, Zhou H

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They also directly influence the hormonal balance in the body, in the absence of which, hormonal intervention is a resort

EDR has been described as a short sequence associated with cerebral-cortex polypeptide complexes