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furthermore, (6) our findings in mice may be translatable to humans, as the metabolic response of diabetic patients undergoing FMD varied as a function of p53 status, and the efficiency of weight loss retention of individuals after bariatric surgery correlated negatively with TREM2 and TP53 e xpression levels in visceral AT

Weber M, Wu T, Hanson JE, Alam NM, Solanoy H, Ngu H, Reeder J (2015) Cognitive deficits, changes in synaptic function, and brain pathology in a mouse model of normal aging