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Description

The gut microbiota regulates the metabolism and side effects of irinotecan (CPT-11), a topoisomerase inhibitor prodrug of SN-38 that is frequently used to treat colorectal cancer (Wallace et al., 2018)

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IGF-1R is a receptor tyrosine kinase that mediates the actions of IGF1, which binds with high affinity, whereas IGF2 and insulin bind to this receptor with low affinity [23]

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Serious semaglutide risks include pancreatitis and gallbladder disease

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