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Methylglyoxal activates NF-kappaB nuclear translocation and induces COX-2 expression via a p38-dependent pathway in synovial cells

Chang, G

Nat Mater 19:900909

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These data extend prior work on SLC25A39 by showing that, in immune cells, SLC25A40 is present at baseline and is inducible by inflammatory stimulation, suggesting a regulatory mode distinct from the post-translational stability mechanism described for SLC25A39, highlighting different modes of control for the two transporters

[24] Artesunate combination drugs have a number of advantages over artemether-based drugs in terms of its uptake and administration routes and may be more effective in treatment of severe and complicated malaria in children