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For comparative SAR studies: identical experimental conditions across MT-1, MT-II, and PT-141 treatment groups are essential for valid potency ratio determinations

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Thus, in the absence of contra-indications, these patients should be treated regardless of the severity of their liver disease and they do not need a liver biopsy of noninvasive assessment of liver fibrosis (Figure 1B)

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4 , 5 Several shuttle transport systems exist across the outer and inner membranes that are essential to the central functions of mitochondria

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