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Training cells at elevated temperatures induces thermotolerance (Glory et al., 2014)

Chronic reliance on antacids suggests inadequately controlled disease requiring more definitive intervention

41,42 Beyond glycolysis, several enzymes in the SCC-distinguishing metabolic gene signature incorporate glucose carbons into metabolites of other pathways (Fig

During ferroptosis, mitochondria not only act as a site for lipid peroxidation but also function as a central hub amplifying death signals ( 4.4 P53 as a bi-functional gatekeeper The tumor suppressor p53 is a pivotal modulator of both ferroptosis and cuproptosis