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Trends Immunol (2012) 33:16873.10.1016/j.it.2012.01.010 4 SchreiberSCrabtreeG

Endothelin-1 (ET-1) is a potent, 21-residue vasoconstrictive peptide that plays a key role in the regulation of vascular tone and cardiovascular homeostasis (Wolf and Beck-Sickinger, 2021)

doi: 10.3748/wjg.v27.i37.6224 52 IinoC.ShimoyamaT.ChindaD.AraiT.ChibaD.NakajiS.et al

Although fundamental 5A-1MQ and LD-mediated changes to the microbiome were identified, this work is similar to many current studies where further investigations will clarify if changes in the microbiome are causative or associative 100

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