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doi: 10.1093/jpp/rgac069 230 WangQQiBShiSJiangWLiDJiangXet al

The idea has been tested in patients following abdominal surgery, and it appeared to be safe but ineffective

In an experiment using hydrogen peroxide to induce oxidative stress in granulosa cells, EVs derived from granulosa cells contain Nrf2mRNA, an mRNA that can activate antioxidant signaling pathways in other cells, particularly oocytes, thus resisting the oxidative stress environment (Saeed-Zidane et al., 2017)