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The amount of -ketobutyrate, which was generated during the enzymatic reaction, was quantified with 3-methyl-2-benzothiazolinone hydrazine hydrochyperlipidemiaoride as the description of previous studies [28]

Often called the "master antioxidant," glutathione is a molecule made of three amino acids: cysteine, glutamate, and glycine

More recently, emerging MRI techniques aimed at directly estimating extracellular pH have further expanded the potential to non-invasively characterise tumour acidity (194, 195), although these remain largely in the early stages of clinical validation

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