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4 GABA levels and pharmacotherapy in ASD clinical applications 4.1 Abnormal GABA levels in the blood of ASD patient A study from Egypt shows that the serum GABA levels in children with ASD are significantly reduced, as are the levels of GABAB receptors, while the serum glutamate levels are significantly increased

Hum Mol Genet 7:20212028 Osman AA, Saito M, Makepeace C, Permutt MA, Schlesinger P, Mueckler M (2003) Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium