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Supplementation of folic acid, vitamin B-12 15 , pyridoxine, betaine, dimethylglycine (DMG), and choline is also known to lower elevated homocysteine levels in most patients with the MTHFR genetic defect

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Similarly, medicinal plants have diverse bioactive compounds that can effectively block these channels and can control seizures

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However, extant human studies on BPC-157 as an anti-ulcer agent indicate a positive safety profile, with no toxicity reported [34]