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Real-time qPCR assays were performed with SYBR Green Supermix (KAPA Biosystems) and a CFX384 Real-Time PCR detection system (BioRad)

Both the percentage of germinated embryos (Fig

Abnormal functioning of serine proteases may contribute to the development of disorders derived from inflammatory cell activation that lead to immunological problems and excessive activation of inflammation and the inhibition of serine proteases by protease inhibitors plays an important role in prevention of these diseases (Clemente and Carmen 2014)

[DOI] [PubMed] [Google Scholar] 25.Xie Y, Wang Q, Wang C, Qi C, Ni Z, Mou S

Therefore, CANA and GLP-1RAs orchestrate pleiotropic therapeutic benefits by converging on mitochondrial quality control, macrophage polarization, and inflammasome-cytokine axis suppression, thereby resolving immunometabolic crossfire in pulmonary systems and positioning these agents as cornerstone therapies for diabetes-related multiorgan inflammatory sequelae