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PI3K/Akt signaling is involved in the pathogenesis of bleomycin-induced pulmonary fibrosis via regulation of epithelial-mesenchymal transition

10.1073/pnas.1820130116 Proc

In PD rat model, Hcy also reduced activity of mitochondrial complex I and caused oxidative stress in the nigrostriatal pathway that were associated with increased production of hydroxyl radicals, reduced glutathione level, and enhanced activity of antioxidant enzymes such as superoxide dismutase and catalase [70]

Table 5 A clinical study reported the effects of sulforaphane on depression outcomes in cardiac patients with mild to moderate depression

Supports antioxidant activity, detox pathways, and healthy cell function

This effect resulted in a potent inhibitory effect of AC on TNBC progression and metastasis