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While this represents a potential confound for metabolite quantification 5 , it also provides an opportunity for simultaneously assessing task-induced BOLD dynamics from unsuppressed water data obtained during the MRS acquisition 6,7

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However, it is important to consider that many chimeric mouse ALS studies use whole-body irradiation as the regimen for bone marrow transplantation, which appears to cause disruptions in the BBB and thus could allow blood-derived monocytes to more freely enter the CNS and mature into microglia

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10.1016/j.canlet.2024.216612 117 WeiS.MaW.XieS.LiuS.XieN.LiW.et al (2023)