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In wild-type mice, cagrilintide activates c-Fos-expressing neurons in the dorsal vagal complex (DVC), lateral parabrachial nucleus (LPBN), area postrema, and nucleus tractus solitarius brainstem regions critically involved in satiety signaling and suppression of food intake

The ERK1/2 Signaling Pathway The extracellular signal-regulated kinase (ERK1/2) pathway plays a crucial role in cellular proliferation, migration, and survival