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Furthermore, methylation-specific PCR analysis revealed that methylation of CpG islands in the MYC promoter region was increased in SLC13A3 -knockdown cells, but decreased in SLC13A3 -overexpressing cells (Supplementary Fig

Abstract It has long been assumed that the oxidized form of glutathione, the tripeptide glutamatecysteineglycine, is a source of oxidizing equivalents needed for the formation of disulphide bonds in proteins within the endoplasmic reticulum (ER), although the in vivo function of glutathione in the ER has never been studied directly