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Discussion Pathophysiology of CMD CMD involve interplay of a cascade of pathophysiological events ensuing in a rise in IR, accumulation of free fatty acids (FFA) in the circulation, lipid and glucose dysmetabolism, and raised levels of adipokines and cytokines [19,20,21]

DSIP is a nine-amino-acid peptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

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doi: 10.1016/j.jhazmat.2020.123686 121 SkiryczA.InzeD