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Conceivably, the elimination of PDPN + cells in the MB TME may reduce the immunosuppression exerted by different types of mesenchymal stromal cells allowing the triggering of NK or T cell responses as shown in other tumor models (278281)

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Metabolic roles of folate coenzymes

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This integrative approach allows for tailored treatments that address the unique needs of each patient, promoting optimal health and well-being