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Following Laviss work, we found that introducing an azetidine group to RT can boost its quantum yield to 2.9%, which is threefolds of that of ThiolQuant Green

DSB recognition by MRN complex The MRN complex, comprising MRE11, RAD50, and NBS1 proteins, is an important DSB sensor, and has intrinsic DNA-binding activity and nucleolytic activities (Paull and Gellert 1998