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When you enter perimenopause, you stop ovulating every month, which causes levels of progesterone to fall

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PLoS ONE 9:e90863 Vasdev S, Gill V, Longerich L, Parai S, Gadag V (2003) Salt-induced hypertension in WKY rats: prevention by alpha-lipoic acid supplementation

As an autoimmune condition, Hashimotos can increase systemic inflammation and affect nerve sensitivity, which may worsen existing nerve pain or make the nervous system more reactive

Purinergic and calcium signaling in macrophage function and plasticity

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