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Description

Iron overload increases ferritin levels and decreases RUNX2 levels in BMSCs, causing irregular morphological changes, significantly reducing their activity, and inhibiting osteogenic differentiation, while melatonin therapy could reverse this process and promote osteogenic differentiation of BMSCs

Moreover, increased levels of LCACs may also induce endoplasmic reticulum (ER) stress and accelerate the progression of cell damage [30]

Integration with Other Technologies ONE Innovation Labs' technology platform extends beyond individual ingredients to comprehensive delivery solutions