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Unlike flavokavain A, flavokavain B induced G2/M cell cycle arrest in cancer cells regardless of the p53 status [128,131,132,134,136,137], which is intriguing given their similar structures (Figure 2)

J Biol Chem 279: 2593525938 Acknowledgements We thank The Wellcome Trust and the Biotechnology and Biological Sciences Research Council for financial support

This gives rise to increased fluorescence

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Presence of histone H3 acetylated at lysine 9 in male germ cells and its distribution pattern in the genome of human spermatozoa

Results Ninety-nine new cases of dementia (including 71 of Alzheimer disease) occurred during the follow-up