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Axitinib reduced the destruction of tight junction proteins and reduced BBB permeability in mice, while increasing spatial awareness, exploration, associative memory, working memory, and lowering -amyloid levels (Yuan, et al

demonstrated that macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques (65)

On the other hand, ROS may have an inhibitory effect on tumor development and metastasis

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According to preliminary estimates, there has been a 26% increase in anxiety disorders and a 28% increase in severe depressive disorders in just 1 year (3)