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As a dynamic and zinc-sensitive organelle, the Golgi apparatus integrates structural, enzymatic and signaling functions that are finely tuned by zinc homeostasis

The liver plays a critical role in energy metabolism

This 2-year-old girl is diagnosed with lymphadenitis, and her father is concerned due to a family history of cancer

Taken together, these data strongly argue against necroptosis as the primary mode of regulated cell death in renal tubules and suggest that the effects in RIPK3-ko and Nec-1-treated mice are due to extratubular effects

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However, excessive ROS accumulation disrupts redox balance, leading to oxidative stress, inflammation, barrier dysfunction, and macromolecular damage, which are closely associated with the pathogenesis of various skin diseases, including psoriasis, atopic dermatitis, pigmentary disorders, photoaging, and skin cancers