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Integrating multi-omics data, a pathway analysis, and computational modeling may offer powerful tools to investigate metabolic reprogramming in ECs during aging and atherosclerosis, as exemplified by Kalucka et al.s single-cell RNA-sequencing (scRNA-Seq) atlas of 11 mouse tissues, which revealed 78 EC subclusters and highlighted tissue origin as the primary determinant of EC heterogeneity, including tissue-specific metabolic profiles [234]

Effects of ascorbic acid on glucose-6-phosphate dehydrogenase-deficient erythrocytes: studies in an animal model

doi: 10.1136/jitc-2020-001369 41 Del PreteASalviVSorianiALaffranchiMSozioFBosisioDet al

In almost every case where glutathione was linked to a severe cardiovascular event, the situation involved: High-dose IV therapy rather than oral supplements

Song F, Chen W, Jia W, Yao P, Nussler AK, Sun X, et al

10.1016/j.ctrv.2008.07.004 30 HanJ.YueX.ChangJ.ShiW.HuaY