glutathione redox biology Disulfide - an overview Glutathione and peroxisome redox homeostasis

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Zhu Y, Tong L, Nie K, Wiwatanaratanabutr I, Sun P, Li Q, et al

In: Chandrasekar R, Tyagi BK, Gui Z, Reeck GR, editors

By integrating metagenomic profiles, we further revealed that gut microbial dysbiosis in RBD-PD and iRBD drives a functional shift away from dietary fiber fermentation and toward enhanced degradation of protein, aromatic amino acids, glycine, and intestinal mucin glycans

Another significant endogenous mechanism is the activity of various oxidase enzymes

51 Inactivation of FXR leads to the hepatic accumulation of some urea cycle precursors, and activation results in an increase in the expression of glutamine synthetase GS) and urea cycle-related genes that promotes glutamine synthesis and urea production