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Ipamorelin is a selective Ghrelin receptor agonist that mimics ghrelin to stimulate the release of growth hormone from the pituitary gland

Conchillo M, De Knegt RJ, Payeras M et al (2005) Insulin-like growth factor I (IGF-I) replacement therapy increases albumin concentration in liver cirrhosis: results of a pilot randomized controlled clinical trial

When the medication becomes less potent, it may deliver a lower dose than intended, making treatment less effective

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It activates the beta-3 adrenergic receptors on fat cells, which triggers the release of stored fat through lipolysis

RANDOMIZED TRIAL OF HIGH DOSE FUROSEMIDE-HYPERTONIC SALINE IN ACUTE DECOMPENSATED HEART FAILURE WITH ADVANCED RENAL DISEASE