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TNBC cells have a strong ability to induce M2 macrophage differentiation, which helps the cells to acquire resistance to immunotherapy and chemotherapy, as well as to bromodomain and extra terminal domain (BET) inhibitors ( 2.2 Tumor-associated neutrophils Neutrophils are the most common cells in the innate immune system

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Tian YG, Yue M, Nashun B, Wu SJ, Gu WW, Wang YJ