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The drug is given by IV infusion in clinic or hospital settings using dosing regimens that may include two doses separated by at least 7 days or a single larger dose, depending on weight and indication

Doses often cited range from 200 to 500 mcg (micrograms) administered daily, although some go up to 1000 mcg

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In StatPearls [Internet]

Effects of CD38 mAbs on CD38 high and CD38 low/- NK cells

[3] The speed of response depends on multiple factors including the severity and duration of deficiency, the presence of neurological complications, and individual metabolic differences