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Upon establishing the kinetics of shRNA-mediated knockdown of these proteins in H1299 cells, we determined the onset of protein depletion to be 48 h post-lentiviral infection (time-point 0) (Fig

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Laboratory evaluation revealed elevated complement component C4a and multi-class mycotoxin positivity, including markedly elevated ochratoxin A

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In the metabolism of amino acids, G-MDSCs upregulate the expression of cationic amino acid transporter 2 (CAT2) and arginase to increase the uptake of L-Arg