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By interpreting the perturbations occurring upon drug treatment at the metabolic pathways level, a more comprehensive understanding of the impact of drugs on the complexity of cells metabolic networks can be achieved

However, GDH2 plays an important role in eliminating the growth-inhibiting effect of IDH1 (R132H) mutant gliomas (134)

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Following Rg1 treatment, iron content, FTL, FTH, and MDA levels in renal tissues were significantly reduced, while GPX4, FSP1, and GSH levels were elevated (Guo et al., 2022)