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In a D-galactose model of accelerated aging, melatonin improved memory through inhibition of microgliosis and downregulation of NF-B and NOS [390]

As for the elderly patients and those with chronic diseases, it takes a longer period of time to generate effective adaptive immune responses due to the deterioration of immune functions

Growing evidence suggests that certain miRNAs play a crucial role in skin aging

PARP-1 inhibitors sensitize HNSCC cells to APR-246 by inactivation of thioredoxin reductase 1 (TrxR1) and promotion of ROS accumulation

Hemoglobin- and myoglobin-induced acute renal failure in rats: Role of iron in nephrotoxicity

Unique non-Hodgkins lymphoma, showing immature lymphoid phenotype, lack of lineage commitment, and N-MYC oncogene amplification