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In contrast to the FAD binding, the NADPH-binding pocket was in a surface-exposed cleft (Fig 2B)

Apart from DSePA, our group has also studied the radioprotective activity of another organoselenium compound, dihydroxy-1-selenolane (DHS), which was earlier reported for GPx-like activity under in vitro conditions by Iwaoka and co-workers [93, 94]

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