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When activated, Nrf2 disassociates from its repressor protein KEAP1 that reacts with oxidative radicals, translocates to the nucleus, binds to antioxidant response element and induces the transcription of defensive genes

Cnops, L., Tannich, E., Polman, K., Clerinx, J

Because Lyme disease can present as three distinct phases, the results of diagnostic laboratory tests may vary based on disease acuity and progression