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2-fPBA would quickly capture the desilylation product of TBSDSA, thus making desilylation a rate-determining step for the two-step D2L reaction (Supplementary Fig

By incorporating microfluidic technology, these chips enable the construction of more precise and controllable organoid models that simulate the microenvironment, vascularization, and tissue interactions (95)

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Some of them were capable of reproducing the features of AD, while others specifically mimicked the cerebrovascular pathology associated with AD, characterized by changes in the anatomical structures of cerebral vessels (Horgusluoglu et al