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Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond

Normal mice in this experiment usually showed less violent movements and were more likely to interact with the newcomer, the intruder 54,55

Relapse after drug discontinuation, development of tolerance, and drug resistance further limit effectiveness

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However, experimental data indicates that a lack of folate could have beneficial effects on cancer while taking folate supplements could accelerate the development or growth of malignancies