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Given that memantine, the glutamate receptor agonist, shows clinical relevance it is now timely to research related pathways, an understanding of which could identify novel approaches to treatment of AD

Additionally, exposure to toxins, liver damage, illness, and genetics can disrupt and impact glutathione production

Retrieved 2 July 2015

Bladder cancer and arsenic through drinking water: a systematic review of epidemiologic evidence

however, glutathione is significantly depleted in hepatocytes during SNMP, which is probably attributed to the hepatocytes inability to overcome the threshold energy necessary for glutathione synthesis under subnormothermic conditions (145)