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Frataxin deficiency in the mitochondrion leads to ISC failure and ROS generation

Downregulation of solute carrier family 7 member 11 (SLC7A11), a component of System Xc-, has been shown to induce ferroptosis (YAO et al., 2021), resulting in an imbalance in the Gln metabolism pathway

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For instance, Hsp70 functions as a chaperone and protects neurons from protein aggregation and toxicity (in PD, AD, polyglutamine diseases, and amyotrophic lateral sclerosis), protects cells from apoptosis (PD), is a stress marker (temporal lobe epilepsy), and also protects cells from cerebral ischemic injury

Additionally, Spirulina has remarkable protein profile, incorporates all eight fundamental amino acids namely, phenylalanine, tryptophan, methionine, leucine, valine, threonine, isoleucine and lysine, just as ten non-fundamental amino acids: aspartic corrosive, arginine, cysteine, proline, glycine, glutamic corrosive, serine, histidine, alanine, and tyrosine (Seyidoglu et al

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