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Pharmacological characterisation of novel adenosine A 3 receptor antagonists

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We have hypothesized that a hybrid ester prodrug (see Figure 1) containing the QM generating moiety that is selectively hydrolyzed and activated by oxidized protein hydrolase (OPH) will deplete intracellular GSH (see Figure 2) and promote oxidative stress induced apoptosis in cancer cells by a mechanism similar to that of NO-ASA, i.e., release of a QM depleting intermediate [23]

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Although inflammation is important in both diseases, the inflammatory response in COPD is markedly different from that in asthma, as summarized in Figure 4-5

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Miyagi SJ, Brown IW, Chock JM, Collier AC

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Brostallicin, a novel anticancer agent whose activity is enhanced upon binding to glutathione

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L-Carnitin: Abnehmen, Energie und Risiken L-Carnitin gilt als beliebter Fatburner und Energielieferant

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