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Glucose clamp technique: a method for quantifying insulin secretion and resistance

Regulation of the homologous -glutamylcysteine synthetase activity in mammals may provide help to ask this question

doi: 10.1007/s12185-019-02806-8, 70

Twelve subjects with normal glucose tolerance were enrolled as a control group

Notably, all the above beneficial effects of metformin were completely abolished upon addition of compound C, a specific inhibitor of AMP-activated protein kinase (AMPK)