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A given allele may be associated with a disease if it is more common in sick people

However, a 2-year treatment with CoQ 10 (300 mg/day) as adjunctive therapy in a randomized, controlled multicenter trial affecting 420 patients suffering from chronic heart failure (Q-SYMBIO trial) demonstrated an improvement in symptoms and reduction in major cardiovascular events (Mortensen et al., 2014)

E., Muller, T

Trends Pharmacol Sci 16: 368374

Although effective in suppressing thyroid hormone synthesis, these treatments may be associated with adverse effects and may not effectively mitigate oxidative or inflammatory complications

Allergies If you are allergic to cobalt, you should not take vitamin B12, as vitamin B12 contains a cobalt molecule