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The detoxification pathway of AFB 1 depends on the conjugation of AFBO with glutathione (GSH), which is catalyzed by glutathione S -transferase (GST) in liver [14]

In the Fenton reaction, iron ions react with hydrogen peroxide to generate highly toxic hydroxyl radicals, directly promoting ferroptosis (Henning et al

The formation of unstable N -glucuronides of aromatic amine containing drugs was previously linked to bladder cancer after hydrolysis back to the parent drug under the acidic conditions in the bladder

Erion, M

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2, 3, 4 Neuroimaging studies have reported reduced vermis volume as well as total cerebellar volume, whereas post-mortem analyses have revealed a significant reduction in the number of Purkinje cells in individuals with autism