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Binding to ocular melanin reportedly can increase brimonidine s absorption and retention based on its marked affinity for melanin-containing ocular tissues in vitro [231]

10.1038/s41467-021-27948-4 145 XiaoJ.ZhangS.TuB.JiangX.ChengS.TangQ.et al (2021)

116 As a p53 target gene, damage-regulated autophagy modulator (DRAM) is an effector of p53-mediated death and encodes a lysosomal protein that promotes autophagy