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For both RF, anti-citrullinated protein Abs and anti-carbamylated protein Abs, the pool of IgG auto-Abs seem to be dominated by the IgG1 and IgG4 subclasses [220,221,222,223]

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Hypervitaminosis B12 can indicate an underlying condition rather than excessive supplementation, but its important to monitor levels with a healthcare professional

The implications of ROS-induced molecular damage and altered redox signaling include bone homeostasis loss, increased pro-inflammatory mediators, and MMP overexpression and activation

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