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doi: 10.1016/j.freeradbiomed.2019.12.007 221 JamillouxYEl JammalTVuittonLGerfaud-ValentinMKereverSSeveP

however, given the nature of the population, this may be unavoidable

DILI in Patients with Disease State Certain disease conditions may predispose individuals to DILI due to alterations in host immune function, drug metabolizing enzyme activity, lower serum albumin, glutathione reserve in the liver and overall ability to scavenge chemically reactive metabolites that can induce hepatotoxicity

This is compounded by a high estimated prevalence of between 3.211.8%, being [4, 5] even greater in certain subgroups such as those with diabetes mellitus (20%) [6] and post radical prostatectomy (16%) [7]

It may be taken directly or mixed with water or juice

(6) Congenital heart defect: Surgery to repair the defect or prescription medications to manage the symptoms