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doi: 10.1016/j.foodchem.2023.135664 14

This epigenetic condition causes differentiation-related genes like CEBPA and RUNX1 to be silenced while stem cell genes like HOXA/B and MEIS1 are persistently activated, ultimately leading to myeloid differentiation blockage (73)

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For example, myeloid-derived suppressor cells (MDSCs) and regulatory T cells (Tregs) are two key types of immunosuppressive cells in the tumor microenvironment and systemic circulation (55)

This suggests that a resistance exercise-related mechanism of inducing plasma NO, perhaps due to increased shear stress that triggered an up-regulation in NO-cGMP signaling, is a conceivable candidate for this response