4-hne glutathion peroxidase The Role of Glutathione Peroxidase-1 in Health and Disease Simplified scheme showing ROS and

We were surprised to see that the COVID-19 patients in the 21 to 40 and the 41 to 60 groups had much less glutathione and more oxidative stress than the corresponding age groups without COVID-19, Sekhar said

Favreau C, Savy C, Bourgoin M, Botton T, Bailly S, Granger F, et al

H2O2 when accumulated is toxic to body tissues or cells

207 Arginine can also increase monocyte migration and proinflammatory factor production in peripheral blood during the early stages of inflammation

So theyre not being killed

Oxidative stress also activates the Kelch-like ECH-associated protein 1 (Keap1)-Nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) redox regulator pathway, releasing Nrf2 to regulate the expression of genes that control antioxidant, inflammatory and immune system responses, facilitating GSH activity