glutathione-responsive prodrug

glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of A glutathione-triggered precision explosive system

Name: glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of A glutathione-triggered precision explosive system
Brand: reganhouse.co.nz
SKU: 85438404997
Price: 27.00 USD
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Rating: 4.5958000000000006 (30 reviews)

A glutathione triggered precision explosive system for improving tumor chemosensitivity Nano Research Springer Nature Link A GSH Activatable Theranostic Prodrug Based on Photoinduced Electron Transfer for Cancer Fluorescence Imaging and Therapy PDF) Glutathione responsive iNOS inhibiting polymeric prodrug for targeted Inhibition of angiogenesis Glutathione responsive prodrug conjugates for image guided combination in cancer therapy ScienceDirect A Mechanism of glutathione driven redox responsive reaction. B Cellular Download Scientific Diagram Synthesis of glutathione responsive, amphiphilic methotrexate based prodrug nanoparticles: In vitro and in vivo assessment against metastatic breast cancer ScienceDirect

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Taking advantage of the fact that they can be reduced by thiols that exist in the cell cytoplasm, such as glutathione, ADCs have been engineered to be conjugated to the disulfide linkers that remain stable in the circulation and selectively release drugs in the cytoplasm